GO:0003700 (term)

DNA-binding transcription factor activity

Definition

(source: GO:0003700)

A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

synonyms: DNA binding transcription factor activity, gene-specific transcription factor activity

Bricks

Brick	Language	Pattern	Categories
BKO:0000521 DNA-binding transcription factor activity (AF main)	AF L1V1.2		BKO:0000573 transcription
BKO:0000524 DNA-binding transcription factor activity (AF synonym 1)	AF L1V1.2		BKO:0000573 transcription
BKO:0000525 DNA-binding transcription factor activity (AF synonym 2)	AF L1V1.2		BKO:0000573 transcription

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